CO-OP Student

Date: Jun 16, 2019

Location: MA, US

Company: MIT Lincoln Laboratory

Group 48—Bioengineering Systems and Technologies

The Bioengineering Systems and Technologies Group seeks to improve the performance of human-centered missions through preventing injury and disease, improving sensing and identification of people and their environment, and speeding rehabilitation and recovery. This goal is accomplished through five broad technical areas: biomedical sensing, neurocognitive technologies, synthetic biology, bioinformatics and biometrics/forensics. Biomedical sensing includes advanced sensors, algorithms, modeling, prototyping, and field testing of technologies to diagnose disease, predict outcomes, avoid injuries, and monitor and enhance human performance. Our applied neurocogntive research enables objective, technology-based enhancements to neurological, cognitive, & psychological health, performance and recovery. The three main neurocognitive goals include increasing cognitive and psychological performance and resilience; measuring, modeling, and modifying the brain to mitigate neurotrauma and neurodegeneration; and developing human-machine interfaces for enhanced performance and communication.  The  synthetic biology research area emphasizes the development of tools and techniques that will greatly speed the design, evaluation, and assessment of genome-wide engineering approaches through highly integrated microfluidic devices. Bioinformatics is applied across the group to uncover signatures in high-throughput genomic, transcriptomic, and proteomic data sets. Biometrics and forensics research is developing technologies and systems for human identification, including rapid DNA analysis, standoff biometric sensing, scientific validation of forensic techniques, and integrated architecture analyses. This highly interdisciplinary group draws on skills from biology, biochemistry, biosignal processing, neuroscience, cognitive science, engineering, computer science, physics, and medical research areas. Primary government sponsors are in the Departments of Defense, Homeland Security, and Justice, as well as the National Institutes of Health.

Job Description

Description:

The Bioengineering Systems and Technology group is seeking a motivated student to assist staff with the design and execution of studies that support our programs utilizing novel, DNA-based systems. MIT LL has current government-sponsored R&D programs developing tools to enable engineered bacterial communities, advanced mammalian cell culture platforms, and high-throughput DNA assembly. The position involves working independently as well on project teams with experts in synthetic biology, molecular biology and bioinformatics to achieve project goals.

Responsibilities:

  • Molecular biology tasks including: DNA amplification, purification, and sequencing/analysis; planning and assembly of DNA constructs, and basic microbiology.
  • Culture and maintenance of mammalian primary cells and cell lines in standard culture and in novel platforms.
  • Troubleshoot issues with experimental design and execution.
  • Summarize data, interpret results, and format data for reporting via presentation or publication.
  • ab organizational functions such as sourcing and preparation of reagents and materials, and calibration/maintenance of instrumentation.

Requirements:

Education:

Currently pursuing B.A. or B.S. in biology, biochemistry, bioengineering or related field.

Experience:

  • Hands-on laboratory experience with molecular and/or synthetic biology.
  • Working knowledge and understanding of a range of basic molecular/synthetic biology techniques.
  • Previous experience with sterile technique and mammalian cell culture is highly desired.


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